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Bacteriocins, also known as antimicrobial peptides, are produced naturally by bacteria. Bacteriocins have antimicrobial activity against bacteria closely related to the producer strain in order to protect their ecological niche.

Drugs have a significant impact on the gut microbiome, but the opposite is also true, gut microbiome has an impact on how the drug fulfills its mission. The onehealth paradigm is once again highlighted as a potential game-changer for treatment efficacy and toxicity elaboration.