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In almost 1 / 4 of the sites monitored worldwide, the concentrations of medicine found in rivers exceed  the levels recommended preserving aquatic biodiversity or to prevent antibiotic resistance: that is one of the outcomes of a study performed through the University of York (United Kingdom), in collaboration with 86 studies institutes, including  the National Research Institute for Agriculture, Food and the Environment (Inrae) in France.

The silent pandemic threat is now well known in the field of infectious disease, but yet still few new antimicrobials are coming on the market. Even if a recent study showed that in 2019, 1,2 Million death was due to resistant bacterial infections and thus more death was attributed to bacterial infection than HIV or Malaria.